Preheat broiler.

In a large mixing bowl, combine the shrimp, olive oil, garlic powder, onion powder, black pepper, and cayenne pepper, if using. Toss to coat thoroughly. 

Spread half the shrimp on a rimmed cookie sheet and broil on the second rack for 4 minutes. Turn the shrimp over and broil until cooked through; be careful not to overcook. Remove to a bowl.

Wipe off the cookie sheet, add the remaining shrimp, and broil as directed above; add to bowl.

Combine the buffalo or hot sauce and butter. Pour about 1/2 cup over the shrimp and toss; add more sauce if necessary to coat thoroughly. Serve with sliced celery sticks and blue cheese dip, or use the shrimp to stuff a po'boy. Serve any remaining sauce on the side.